UniProt Summary Literature Review Cleavage Sites Topological Domains Proteolytic Cleavage Secretome Detection
UniProt Summary
UniProt ID

P97333
Entry Name

NRP1_MOUSE
Protein Name

Neuropilin-1
Primary Gene Name

Nrp1
Organism

Mus musculus (Mouse)
Molecular Function

Developmental protein
Receptor
Heparin-binding
Membrane Location

Cell membrane
Membrane



Biological Literature Report of Shedding
Substrate Name neuropilin(NRP-1)
Cell Type
Substrate Description receptor involved in the development of the cardiovascular system, in angiogenesis
Substrate Function Category angiogenesis
Substrate Function Subtype
Sheddase ADAM10
Shedding-related Disease cell receptor
Short Summary of Papers shedding might decrease the availability on cells and simultaneously generate soluble decoys that could intercept VEGF-A signaling
Cleavage Information ZNo-Human:
PMID 18818406



Cleavage Site Diagram



Topological Domains
Topological Domains
 		Start End
Extracellular
 		22 856
Transmembrane
 		857 879



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information ADAM10 18818406   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
PAPER neuron 22728825
PAPER macrophage 24396086