UniProt Summary
UniProt ID

P78380

Entry Name

OLR1_HUMAN

Protein Name

Oxidized low-density lipoprotein receptor 1

Primary Gene Name

OLR1

Organism

Homo sapiens (Human)

Molecular Function

Receptor

Membrane Location

Secreted
Cell membrane
Membrane




Biological Literature Report of Shedding
Substrate Name LOX-1
Cell Type endothelial cells,monocytes
Substrate Description Leukocyte Recruitment - Tethering and rolling
Substrate Function Category Immune and Inflammation
Substrate Function Subtype Immune and Inflammation; receptor (oxdized lipoprotein)
Sheddase unknown
Shedding-related Disease cell receptor
Short Summary of Papers de-adhesion, increase rolling velocity, inhibit ox-LDL & apoptotic cell uptake
Cleavage Information NONE
PMID 16565325 16061745



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
Transmembrane
37 57
Extracellular
58 273



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER ISAR*QQAE 88 UNKNOWN Mass spectrometry 33796845   
PMAP No_information NONE This_entry_is_based_on_an_experiment. Others 16061745   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
SPD 22728825
Sys-BodyFluid Urine 16335936
Sys-BodyFluid Urine 16948836
HCSD cancer(23 cancer cell lines) 20124221
HCSD cancer(colorectal cancer 24418523
HCSD non-small cell lung cancer 21262398