|
|
||
|---|---|---|
| UniProt ID |
P70232 |
|
| Entry Name |
NCHL1_MOUSE |
|
| Protein Name |
Neural cell adhesion molecule L1-like protein |
|
| Primary Gene Name |
Chl1 |
|
| Organism |
Mus musculus (Mouse) |
|
| Molecular Function |
Developmental protein |
|
| Membrane Location |
Secreted |
|
|
|
|---|
| Substrate Name | Neural cell adhesion molecule L1-like protein precursor (CHL1) | |
| Cell Type | COS-7 cells, CHOK1 cells | |
| Substrate Description | neurite growth (promote) | |
| Substrate Function Category | central nervous system (neuron) | |
| Substrate Function Subtype | Central nervous system (CNS) pathology; cell adhesion molecules | |
| Sheddase | ADAM8 | |
| Shedding-related Disease | cell adhesion molecule | |
| Short Summary of Papers | releases soluble fragments relevant for its physiological function. promotes neurite outgrowth and suppresses neuronal cell death | |
| Cleavage Information | ZNo-human;O00533 | |
| PMID | 14761956 |
|
|
|---|
|
|
||
|---|---|---|
|
|
Start | End |
|
|
26 | 1083 |
|
|
1084 | 1104 |
|
|
||||||||
|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | SWKP*QGAP | 753 | ADAM8 peptidase | physiologically relevant | N-terminal sequencing | 14761956 | ||
| MEROPS | VLVP*GAEH | 1040 | ADAM8 peptidase | physiologically relevant | N-terminal sequencing | 14761956 | ||
| MEROPS | SIFQ*DVIE | 1061 | BACE1 | physiologically relevant | N-terminal sequencing | 22692213 | ||
| PaperC | No_information | BACE1 | Type I | proteomics | 22728825 | |||
| PaperC | No_information | BACE2 | Type I TMP | proteomics | 23430253 | |||