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| UniProt ID |
P54763 |
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| Entry Name |
EPHB2_MOUSE |
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| Protein Name |
Ephrin type-B receptor 2 |
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| Primary Gene Name |
Ephb2 |
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| Organism |
Mus musculus (Mouse) |
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| Molecular Function |
Tyrosine-protein kinase |
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| Membrane Location |
Cell membrane |
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| Substrate Name | EphB2 receptor | |
| Cell Type | ||
| Substrate Description | receptor tyrosine kinase binds ephrin-B family ligands. axon guidance during development | |
| Substrate Function Category | central nervous system (neuron) | |
| Substrate Function Subtype | ||
| Sheddase | MMP2, MMP9 | |
| Shedding-related Disease | cell receptor (Eph) | |
| Short Summary of Papers | cleavage of EphB2 induced by receptor-ligand interactions triggers cell-repulsive responses. | |
| Cleavage Information | ZNo-Human: | |
| PMID | 18713744 |
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Start | End |
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19 | 543 |
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544 | 564 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | VYNI* | 360 | MMP2,MMP9 | mutagenesis | 18713744 | |||
| PAPER | ISDL* | 398 | MMP2,MMP9 | mutagenesis | 18713744 | |||
| MEROPS | KLPL*IVGS | 543 | ADAM10 peptidase | physiologically relevant | NONE | 17428795 | ||
| MEROPS | NRRG*FERA | 569 | presenilin 1 | physiologically relevant | Mass spectroscopy | 17428795 | ||
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| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| NO_DATA | NO_DATA | NO_DATA | |