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|---|---|---|
| UniProt ID |
P54762 |
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| Entry Name |
EPHB1_HUMAN |
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| Protein Name |
Ephrin type-B receptor 1 |
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| Primary Gene Name |
EPHB1 |
|
| Organism |
Homo sapiens (Human) |
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| Molecular Function |
Kinase |
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| Membrane Location |
Cell membrane |
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| Substrate Name | EPHB1 | |
| Cell Type | ||
| Substrate Description | axon guidance, nervous system development | |
| Substrate Function Category | central nervous system (neuron) | |
| Substrate Function Subtype | Central nervous system (CNS) pathology; receptor | |
| Sheddase | MMP2, | |
| Shedding-related Disease | cell receptor (Eph) | |
| Short Summary of Papers | MMP2 selective cleavage of Eph B1 | |
| Cleavage Information | NONE | |
| PMID | 12591933 |
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|---|---|---|
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Start | End |
|
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18 | 540 |
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541 | 563 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | AVAA*MEET | 17 | signal peptidase complex (animal) | physiologically relevant | N-terminal sequencing | 15340161 | ||
| ASCENT | ATKK*SAFW | 125 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| MEROPS | YKSE*LREQ | 534 | matrix metallopeptidase-2 | physiologically relevant | NONE | 11694539 | ||
| PMAP | YKSE*LREQ | 534 | matrix metallopeptidase-2 | N-terminal sequencing | 12591933 | |||