UniProt Summary Literature Review Cleavage Sites Topological Domains Proteolytic Cleavage Secretome Detection
UniProt Summary
UniProt ID

P52801
Entry Name

EFNA2_MOUSE
Protein Name

Ephrin-A2
Primary Gene Name

Efna2
Organism

Mus musculus (Mouse)
Molecular Function

Membrane Location

Cell membrane
Membrane



Biological Literature Report of Shedding
Substrate Name Ephrin-A2
Cell Type Neuro-2a cells
Substrate Description neurite outgrowth
Substrate Function Category central nervous system (neuron)
Substrate Function Subtype Central nervous system (CNS) pathology; ligand
Sheddase ADAM10
Shedding-related Disease ligand
Short Summary of Papers ephrin-A2 cleavage may provide a means for axon detachment and termination of signaling.
Cleavage Information NONE
PMID 10958785



Cleavage Site Diagram



Topological Domains
Topological Domains
 		Start End
NO_INFO



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information ADAM10 Gel electrophoresis 10958785   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
SPD 22728825