UniProt Summary Literature Review Cleavage Sites Topological Domains Proteolytic Cleavage Secretome Detection
UniProt Summary
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Biological Literature Report of Shedding
Substrate Name MT3-MMP (MMP-16)
Cell Type Monkey kidney immortalized BS-C-1 (CCL-26), kidney immortalized COS-1 (CRL-1650), and CV-1 (CCL-70) cells; human HeLa S3 cells and fibrosarcoma HT-1080 (CCL-121) cells
Substrate Description
Substrate Function Category
Substrate Function Subtype
Sheddase MT3-MMP
Shedding-related Disease
Short Summary of Papers MT3-MMP is involved in the complex that activates pro-MMP-2
Cleavage Information
PMID 14681236



Cleavage Site Diagram



Topological Domains
Topological Domains
 		Start End
Extracellular
 		120 564
Transmembrane
 		565 585



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
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