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|---|---|---|
| UniProt ID |
P49772 |
|
| Entry Name |
FLT3L_MOUSE |
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| Protein Name |
Fms-related tyrosine kinase 3 ligand |
|
| Primary Gene Name |
Flt3lg |
|
| Organism |
Mus musculus (Mouse) |
|
| Molecular Function |
Cytokine |
|
| Membrane Location |
Secreted |
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|---|
| Substrate Name | FLT3 ligand (FLT3L) | |
| Cell Type | ||
| Substrate Description | hematopoiesis,stimulates the proliferation of early hematopoietic cells by activating FLT3 | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | ||
| Sheddase | ADAM17 | |
| Shedding-related Disease | ligand | |
| Short Summary of Papers | FLT3L undergo ectodomain shedding by ADAM17 | |
| Cleavage Information | ZNo-Human: | |
| PMID | 15077180 |
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|---|---|---|
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Start | End |
|
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27 | 189 |
|
|
190 | 210 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | SPIA*LEAT | 176 | ADAM17 | 15077180 | ||||
| PAPER | PIAL*EATE | 177 | ADAM17 | 15077180 | ||||