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| UniProt ID |
P48023 |
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| Entry Name |
TNFL6_HUMAN |
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| Protein Name |
Tumor necrosis factor ligand superfamily member 6 |
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| Primary Gene Name |
FASLG |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function |
Cytokine |
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| Membrane Location |
Secreted |
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| Substrate Name | Fas ligand | |
| Cell Type | endothelial cell, monocytes, lymphocytes, neutrophils | |
| Substrate Description | Leukocyte Recruitment - Leukocyte and endothelial cell activation and immune modulation | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | Immune and Inflammation; cytokine | |
| Sheddase | MMP7 | |
| Shedding-related Disease | cytokine | |
| Short Summary of Papers | inhibit cytotoxic activity | |
| Cleavage Information | NONE | |
| PMID | 16565325 11212252 |
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Start | End |
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81 | 102 |
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103 | 281 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | LQKE*LAEL | 110 | matrix metallopeptidase-7 | physiologically relevant | NONE | 12464266 | ||
| PMAP | LQKE*LAEL | 110 | matrix metallopeptidase-7 | This entry is based on an experiment | Mutagenesis | 12464266 11212252 16474169 | ||
| MEROPS | ELAE*LRES | 113 | matrix metallopeptidase-7 | physiologically relevant | NONE | 12464266 | ||
| PMAP | ELAE*LRES | 113 | matrix metallopeptidase-7 | This entry is based on an experiment | Mutagenesis | 12464266 11212252 | ||
| MEROPS | TASS*LEKQ | 126 | matrix metallopeptidase-7 | physiologically relevant | NONE | 12464266 | ||
| PMAP | TASS*LEKQ | 126 | matrix metallopeptidase-7 | This entry is based on an experiment | Mutagenesis | 12464266 11212252 | ||
| PMAP | EKKE*LRKV | 142 | matrix metallopeptidase-7 | This entry is a predicted | Mutagenesis | 12464266 11212252 | ||
| PAPER | No-information | ADAM10 | NONE | NONE | 17290285 | |||