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|---|---|---|
| UniProt ID |
P43489 |
|
| Entry Name |
TNR4_HUMAN |
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| Protein Name |
Tumor necrosis factor receptor superfamily member 4 |
|
| Primary Gene Name |
TNFRSF4 |
|
| Organism |
Homo sapiens (Human) |
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| Molecular Function |
Host cell receptor for virus entry |
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| Membrane Location |
Membrane |
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| Substrate Name | OX40 | |
| Cell Type | adult T-cell leukemia (ATL) cells | |
| Substrate Description | ||
| Substrate Function Category | ||
| Substrate Function Subtype | ||
| Sheddase | matrix metalloproteinase (possible) | |
| Shedding-related Disease | adult T-cell leukemia | |
| Short Summary of Papers | high level of soluble OX40 are shed into blood from ATL cells; soluble OX40 may be a diagnostic biomarker for acute adult T-cell leukemia | |
| Cleavage Information | ||
| PMID | 30652238 |
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|---|---|---|
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Start | End |
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29 | 214 |
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215 | 235 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | TVTG*LHCV | 28 | unknown peptidase | physiologically relevant | Mass spectroscopy | 26796116 | ||