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| UniProt ID |
P42081 |
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| Entry Name |
CD86_HUMAN |
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| Protein Name |
T-lymphocyte activation antigen CD86 |
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| Primary Gene Name |
CD86 |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function |
Host cell receptor for virus entry |
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| Membrane Location |
Cell membrane |
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| Substrate Name | CD86 | |
| Cell Type | ||
| Substrate Description | receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | ||
| Sheddase | (unknown) | |
| Shedding-related Disease | cell receptor | |
| Short Summary of Papers | soluble CD86 can be produced either by the shedding of the membrane form or through an alternative mRNA and detected in human serum. soluble CD86 appears to be a functional costimulatory molecule playing a potentially important role in immune surveillance. | |
| Cleavage Information | NONE | |
| PMID | 11021528 |
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Start | End |
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24 | 247 |
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248 | 268 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | No_information | (unknown) | 11021528 | |||||