UniProt Summary Literature Review Cleavage Sites Topological Domains Proteolytic Cleavage Secretome Detection
UniProt Summary
UniProt ID

P41217
Entry Name

OX2G_HUMAN
Protein Name

OX-2 membrane glycoprotein
Primary Gene Name

CD200
Organism

Homo sapiens (Human)
Molecular Function

Membrane Location

Cell membrane
Membrane



Biological Literature Report of Shedding
Substrate Name OX-2 membrane glycoprotein (CD200)
Cell Type
Substrate Description T-cell proliferation, immunoregulatory function
Substrate Function Category disease
Substrate Function Subtype
Sheddase ADAM28
Shedding-related Disease cancer (chronic lymphocytic leukemia)
Short Summary of Papers sCD200 as a novel prognostic marker and therapeutic target for CLL (chronic lymphocytic leukemia)
Cleavage Information NONE
PMID 11309369 22875025



Cleavage Site Diagram



Topological Domains
Topological Domains
 		Start End
Extracellular
 		31 232
Transmembrane
 		233 259



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information ADAM28 11309369   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
Sys-BodyFluid Cerebrospinal fluid 18052119