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| UniProt ID |
P35613 |
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| Entry Name |
BASI_HUMAN |
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| Protein Name |
Basigin |
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| Primary Gene Name |
BSG |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function |
Host cell receptor for virus entry |
|
| Membrane Location |
Cell membrane |
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| Substrate Name | Basigin (EMMPRIN,CE9,CD147) | |
| Cell Type | ||
| Substrate Description | monocarboxylate transporters targeting, spermatogenesis, embryo implantation, neural network formation | |
| Substrate Function Category | enzyme Inducer | |
| Substrate Function Subtype | cell surface protein; monocarboxylate transporters targeting | |
| Sheddase | MTMMP1 | |
| Shedding-related Disease | MMP Inducer | |
| Short Summary of Papers | proteolytic cleavage of membrane-associated EMMPRIN release soluble EMMPRIN act in a paracrine fashion; endoproteolytic cleavage in the extracellular domain of the integral plasma membrane protein CE9 precedes its redistribution from the posterior to the anterior tail of the rat spermatozoon during epididymal maturation. | |
| Cleavage Information | NONE | |
| PMID | 14985463 17050542 1714914 |
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Start | End |
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138 | 323 |
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324 | 344 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | VLEP*GTVF | 139 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | LEPG*TVFT | 140 | UNKNOWN | Mass spectrometry | 33796845 | |||
| MEROPS | TGHR*WLKG | 170 | human airway trypsin-like peptidase | not physiologically relevant | Mass spectroscopy | 25211023 | ||
| MEROPS | LPEP*MGTA | 209 | membrane-type matrix metallopeptidase-1 | physiologically relevant | NONE | 14985463 | ||
| PMAP | LPEP*MGTA | 209 | membrane-type matrix metallopeptidase-1 | This entry is based on an experiment | N-terminal sequencing | 14985463 17050542 | ||
| PAPER | PEPM*GTAN | 210 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | EPMG*TANI | 211 | UNKNOWN | Mass spectrometry | 33796845 | |||
| ASCENT | MGTA*NIQL | 213 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| MEROPS | GTAN*IQLH | 214 | membrane-type matrix metallopeptidase-1 | physiologically relevant | NONE | 14985463 | ||
| PMAP | GTAN*IQLH | 214 | membrane-type matrix metallopeptidase-1 | This entry is based on an experiment | N-terminal sequencing | 14985463 17050542 | ||
| MEROPS | SESR*FFVS | 273 | trypsin 1 | not physiologically relevant | Mass spectroscopy | 18500335 | ||
| MEROPS | SQGR*SELH | 282 | trypsin 1 | not physiologically relevant | Mass spectroscopy | 18500335 | ||
| ASCENT | GRSE*LHIE | 284 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| ASCENT | LHIE*NLNM | 288 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
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|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| Sys-BodyFluid | Amniotic fluid | 17495049 | |
| Sys-BodyFluid | Cerebrospinal fluid | 17022648 | |
| Sys-BodyFluid | Urine | 16948836 | |
| HCSD | cancer (gastric cancer) | 23161554 | |
| HCSD | cancer (lung cancer) | 19776420 | |
| HCSD | cancer(prostate cancer) | 22908226 | |
| HCSD | cancer(23 cancer cell lines) | 20124221 | |
| HCSD | cancer(Head and neck squamous cell carcinoma) | 23665456 | |
| HCSD | cancer(colon tumor) | 23684732 | |
| HCSD | cancer(colorectal cancer | 22408128 | |
| HCSD | cancer(colorectal cancer | 24418523 | |
| HCSD | cancer(head and neck squamous cell carcinoma) | 22918226 | |
| HCSD | cancer(urothelial carcinoma) | 23591195 | |
| HCSD | cancer(glioblastoma multiforme) | 21574646 | |
| HCSD | cancer(pancreatic cancer) | 21625447 | |
| HCSD | cancer(ovarian cancer) | 23805888 | |
| HCSD | cancer(oral cancer ) | 21714544 | |
| HCSD | cancer(gastric cancer) | 22204653 | |
| HCSD | cancer(Liver metastasis in colorectal cancer) | 23443137 | |
| HCSD | cancer(non small cell lung cancer) | 19655816 | |
| HCSD | cancer(colorectal cancer) | 24681409 | |
| HCSD | cancer(colorectal cancer) | 25216327 | |
| HCSD | cancer(lung adenocarcinoma) | 22896658 | |