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| UniProt ID |
P35456 |
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| Entry Name |
UPAR_MOUSE |
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| Protein Name |
Urokinase plasminogen activator surface receptor |
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| Primary Gene Name |
Plaur |
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| Organism |
Mus musculus (Mouse) |
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| Molecular Function |
Receptor |
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| Membrane Location |
Secreted |
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| Substrate Name | urokinase-type plasminogen activator receptor(uPAR,CD87) | |
| Cell Type | ||
| Substrate Description | angiogenesis; cell migration | |
| Substrate Function Category | angiogenesis | |
| Substrate Function Subtype | angiogenesis; receptor ((GPI)-anchored) | |
| Sheddase | MMP12 | |
| Shedding-related Disease | cell receptor | |
| Short Summary of Papers | antiangiogenic capacity of MMP12 to reduce the number of functional u-PARs by shedding and release the D1 domain of u-PAR | |
| Cleavage Information | GPI-anchor | |
| PMID | 11342439 |
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Start | End |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | PGAR*GRAF | 107 | urokinase-type plasminogen activator | physiologically relevant | NONE | 12195704 | ||
| MEROPS | PGAR*GRAF | 107 | plasmin | physiologically relevant | NONE | 12195704 | ||
| PMAP | PGAR*GRAF | 107 | u-plasminogen activator | This_entry_is_based_on_an_experiment. | Mass spectrometry | 12195704 | ||
| MEROPS | ARGR*AFPQ | 109 | plasmin | physiologically relevant | NONE | 12195704 | ||
| PMAP | ARGR*AFPQ | 109 | plasmin | This_entry_is_based_on_an_experiment. | Mass spectrometry | 12195704 | ||
| MEROPS | RAFP*QGRY | 112 | matrix metallopeptidase-12 | physiologically relevant | NONE | 12195704 | ||
| PMAP | RAFP*QGRY | 112 | matrix metallopeptidase-12 | This_entry_is_based_on_an_experiment. | Mass spectrometry | 12195704 | ||
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| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| SPD | 22728825 | ||