UniProt Summary
UniProt ID

P32942

Entry Name

ICAM3_HUMAN

Protein Name

Intercellular adhesion molecule 3

Primary Gene Name

ICAM3

Organism

Homo sapiens (Human)

Molecular Function

Membrane Location

Membrane




Biological Literature Report of Shedding
Substrate Name ICAM-3(CD50)
Cell Type
Substrate Description ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) and integrin alpha-D/beta-2.
Substrate Function Category Immune and Inflammation
Substrate Function Subtype
Sheddase (unknown)
Shedding-related Disease cell adhesion molecule
Short Summary of Papers the shed sCD50 could be used as a marker of lymphocyte stimulation
Cleavage Information NONE
PMID 7876564



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
Extracellular
30 485
Transmembrane
486 510



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information (unknown) 7876564   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
SPD 22728825
Sys-BodyFluid Plasma/Serum 14718574
HCSD cancer(23 cancer cell lines) 20124221
locate 17986452