|
|
||
|---|---|---|
| UniProt ID |
P30530 |
|
| Entry Name |
UFO_HUMAN |
|
| Protein Name |
Tyrosine-protein kinase receptor UFO |
|
| Primary Gene Name |
AXL |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function |
Tyrosine-protein kinase |
|
| Membrane Location |
Cell membrane |
|
|
|
|---|
| Substrate Name | Axl | |
| Cell Type | ||
| Substrate Description | regulating many physiological processes in cell survival, cell proliferation, migration and differentiation | |
| Substrate Function Category | enzyme | |
| Substrate Function Subtype | receptor (Tyrosine-protein kinase receptor) | |
| Sheddase | ADAM10 | |
| Shedding-related Disease | receptor tyrosine kinase | |
| Short Summary of Papers | produce soluble form of Axl by proteolytic cleavage | |
| Cleavage Information | NONE | |
| PMID | 7822279 16227584 |
|
|
|---|
|
|
||
|---|---|---|
|
|
Start | End |
|
|
26 | 451 |
|
|
452 | 472 |
|
|
||||||||
|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | GTQA*EESP | 32 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | No_information | (unkown) | 7822279 | |||||
|
|
|||
|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| PAPER | cancer(ovary) | 18560578 | |
| Sys-BodyFluid | Amniotic fluid | 17495049 | |
| Sys-BodyFluid | Cerebrospinal fluid | 18052119 | |
| Sys-BodyFluid | Cerebrospinal fluid | 17022648 | |
| Sys-BodyFluid | Urine | 11680902 | |
| Sys-BodyFluid | Urine | 16335936 | |
| Sys-BodyFluid | Urine | 16281181 | |
| Sys-BodyFluid | Urine | 16948836 | |
| HCSD | cancer (gastric cancer) | 23161554 | |
| HCSD | cancer (lung cancer) | 19776420 | |
| HCSD | cancer(prostate cancer) | 22908226 | |
| HCSD | cancer(23 cancer cell lines) | 20124221 | |
| HCSD | cancer(Head and neck squamous cell carcinoma) | 23665456 | |
| HCSD | cancer(colorectal cancer | 22408128 | |
| HCSD | cancer(colorectal cancer | 24418523 | |
| HCSD | cancer(head and neck squamous cell carcinoma) | 22918226 | |
| HCSD | cancer(urothelial carcinoma) | 23591195 | |
| HCSD | cancer(glioblastoma multiforme) | 21574646 | |
| HCSD | cancer(pancreatic cancer) | 21625447 | |
| HCSD | cancer(ovarian cancer) | 23805888 | |
| HCSD | cancer(ovarian cancer) | 22623176 | |
| HCSD | cancer(oral cancer ) | 21714544 | |
| HCSD | non-small cell lung cancer | 21262398 | |
| HCSD | cancer(non small cell lung cancer) | 19655816 | |
| locate | 17986452 | ||