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|---|---|---|
| UniProt ID |
P26842 |
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| Entry Name |
CD27_HUMAN |
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| Protein Name |
CD27 antigen |
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| Primary Gene Name |
CD27 |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function |
Receptor |
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| Membrane Location |
Membrane |
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| Substrate Name | CD27 | |
| Cell Type | ||
| Substrate Description | receptor for CD70/CD27L. play a role in survival of activated T-cells. | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | ||
| Sheddase | (unknown) | |
| Shedding-related Disease | cell receptor | |
| Short Summary of Papers | transmembrane CD27 gives rise to soluble sCD27 most likely via a proteolytic event, that does not involve receptor internalization | |
| Cleavage Information | NONE | |
| PMID | 1311261 |
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Start | End |
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20 | 191 |
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192 | 212 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | VGLS*ATPA | 19 | signal peptidase complex (animal) | physiologically relevant | N-terminal sequencing | 15340161 | ||
| PAPER | No_information | (unknown) | 1311261 | |||||
| PMAP | No_information | gingipain R | This entry is based on an experiment | Gel electrophoresis | NONE | |||
| PMAP | No_information | gingipain K | This entry is based on an experiment | Gel electrophoresis | 17937677 | |||