UniProt Summary
UniProt ID

P26453

Entry Name

BASI_RAT

Protein Name

Basigin

Primary Gene Name

Bsg

Organism

Rattus norvegicus (Rat)

Molecular Function

Receptor

Membrane Location

Cell membrane
Membrane




Biological Literature Report of Shedding
Substrate Name Basigin (EMMPRIN,CE9,CD147)
Cell Type
Substrate Description monocarboxylate transporters targeting, spermatogenesis, embryo implantation, neural network formation
Substrate Function Category enzyme Inducer
Substrate Function Subtype cell surface protein; monocarboxylate transporters targeting
Sheddase MTMMP1
Shedding-related Disease MMP Inducer
Short Summary of Papers proteolytic cleavage of membrane-associated EMMPRIN release soluble EMMPRIN act in a paracrine fashion; endoproteolytic cleavage in the extracellular domain of the integral plasma membrane protein CE9 precedes its redistribution from the posterior to the anterior tail of the rat spermatozoon during epididymal maturation.
Cleavage Information NONE
PMID 14985463 17050542 1714914



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
Extracellular
23 326
Transmembrane
327 347



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information (unknown) 1714914   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
SPD 22728825