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| UniProt ID |
P25942 |
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| Entry Name |
TNR5_HUMAN |
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| Protein Name |
Tumor necrosis factor receptor superfamily member 5 |
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| Primary Gene Name |
CD40 |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function |
Receptor |
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| Membrane Location |
Secreted |
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| Substrate Name | CD40 | |
| Cell Type | endothelial cell, monocytes, lymphocytes | |
| Substrate Description | Leukocyte Recruitment, Leukocyte and endothelial cell activation and immune modulation | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | Immune and Inflammation; cytokine receptor | |
| Sheddase | ADAM17 | |
| Shedding-related Disease | cytokine receptor | |
| Short Summary of Papers | soluble antagonist of immune response | |
| Cleavage Information | NONE | |
| PMID | 16565325 12810728 |
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Start | End |
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21 | 193 |
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194 | 215 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | AVHP*EPPT | 20 | signal peptidase complex (animal) | physiologically relevant | N-terminal sequencing | 11676606 | ||
| PMAP | No_information | ADAM10 peptidase | This entry is based on an experiment | Gel electrophoresis | 16963006 | |||
| PMAP | No_information | ADAM10 peptidase | This entry is based on an experiment | Gel electrophoresis | 16963006 | |||