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|---|---|---|
| UniProt ID |
P24394 |
|
| Entry Name |
IL4RA_HUMAN |
|
| Protein Name |
Interleukin-4 receptor subunit alpha |
|
| Primary Gene Name |
IL4R |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function |
Receptor |
|
| Membrane Location |
Secreted |
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|---|
| Substrate Name | IL-4R | |
| Cell Type | ||
| Substrate Description | receptor for both interleukin 4 and interleukin 13 | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | ||
| Sheddase | metalloproteinase | |
| Shedding-related Disease | cytokine receptor | |
| Short Summary of Papers | sIL-4R is produced by proteolytic cleavage of the cell surface receptor and may be regarded as an immunoregulatory molecule due to its IL-4-antagonizing activity | |
| Cleavage Information | NONE | |
| PMID | 10341317 |
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|---|---|---|
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Start | End |
|
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26 | 232 |
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|
233 | 256 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | No_information | metalloproteinase | 10341317 | |||||