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UniProt ID |
P21926 |
|
Entry Name |
CD9_HUMAN |
|
Protein Name |
CD9 antigen |
|
Primary Gene Name |
CD9 |
|
Organism |
Homo sapiens (Human) |
|
Molecular Function | ||
Membrane Location |
Secreted |
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Substrate Name | CD9 | |
Cell Type | ||
Substrate Description | platelet activation and aggregation.cell adhesion, cell motility and tumor metastasis | |
Substrate Function Category | disease | |
Substrate Function Subtype | ||
Sheddase | (unknown) | |
Shedding-related Disease | cancer (leukaemia) | |
Short Summary of Papers | shedding of CD9 antigen by leukemic cells may enable the clinical monitoring of residual leukemic cell burden | |
Cleavage Information | NONE | |
PMID | 1390240 8180600 |
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Start | End |
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13 | 33 |
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34 | 55 |
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56 | 76 |
|
88 | 111 |
|
112 | 195 |
|
196 | 221 |
|
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Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
MEROPS | M*PVKG | 1 | unknown peptidase | physiologically relevant | N-terminal sequencing | 2358073    | ||
PAPER | No_information | (unknown) | 1390240    8180600    |
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Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
PAPER | platelet | 20962327 | |
SPD | 22728825 | ||
Sys-BodyFluid | Milk | 16502470 | |
Sys-BodyFluid | Seminal Fluid | 16709260 | |
Sys-BodyFluid | Saliva | 17614365 | |
Sys-BodyFluid | Saliva | 18361515 | |
Sys-BodyFluid | Urine | 16948836 | |
Sys-BodyFluid | Plasma/Serum | 18793429 | |
HCSD | cancer (gastric cancer) | 23161554 | |
HCSD | cancer (lung cancer) | 19776420 | |
HCSD | cancer(prostate cancer) | 22908226 | |
HCSD | cancer(23 cancer cell lines) | 20124221 | |
HCSD | cancer(Head and neck squamous cell carcinoma) | 23665456 | |
HCSD | cancer(pancreatic cancer) | 16215274 | |
HCSD | cancer(colon tumor) | 23684732 | |
HCSD | cancer(colorectal cancer | 22408128 | |
HCSD | cancer(colorectal carsinoma) | 23585443 | |
HCSD | cancer(colorectal cancer | 24418523 | |
HCSD | cancer(head and neck squamous cell carcinoma) | 22918226 | |
HCSD | cancer(urothelial carcinoma) | 23591195 | |
HCSD | cancer(glioblastoma multiforme) | 21574646 | |
HCSD | cancer(ovarian cancer) | 23805888 | |
HCSD | cancer(Lung adenocarcinoma) | 22985211 | |
HCSD | cancer(Liver metastasis in colorectal cancer) | 23443137 | |
HCSD | cancer(non small cell lung cancer) | 19655816 | |
HCSD | cancer(colorectal cancer) | 25216327 |