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| UniProt ID |
P20826 |
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| Entry Name |
SCF_MOUSE |
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| Protein Name |
Kit ligand |
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| Primary Gene Name |
Kitlg |
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| Organism |
Mus musculus (Mouse) |
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| Molecular Function |
Growth factor |
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| Membrane Location |
Secreted |
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| Substrate Name | Kit ligand, stem cell factor (SCF) | |
| Cell Type | ||
| Substrate Description | Kit Signaling in cell survival and proliferation, development, hematopoiesis | |
| Substrate Function Category | growth factor & growth hormone | |
| Substrate Function Subtype | growth factor (Kit) | |
| Sheddase | ADAM17 | |
| Shedding-related Disease | growth factor (kit) | |
| Short Summary of Papers | shedding of Kit ligand (Kitl), produce soluble form of growth factor | |
| Cleavage Information | NONE | |
| PMID | 17344430 |
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Start | End |
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26 | 214 |
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215 | 237 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | LVKT*KEIC | 25 | signal peptidase complex (animal) | physiologically relevant | N-terminal sequencing | 1698553 | ||
| MEROPS | PPVA*ASSL | 189 | ADAM9 peptidase | physiologically relevant | NONE | 17344430 | ||
| PMAP | PPVA*ASSL | 189 | ADAM9 peptidase | This_entry_is_based_on_an_experiment. | Gel electrophoresis | 17344430 9920899 | ||
| MEROPS | PVAA*SSLR | 190 | ADAM33 peptidase | not physiologically relevant | NONE | 14676211 | ||
| MEROPS | PVAA*SSLR | 190 | ADAM8 peptidase | physiologically relevant | NONE | 17344430 | ||
| MEROPS | PVAA*SSLR | 190 | ADAM9 peptidase | physiologically relevant | NONE | 17344430 | ||
| MEROPS | PVAA*SSLR | 190 | ADAM19 peptidase | physiologically relevant | NONE | 17344430 | ||
| MEROPS | PVAA*SSLR | 190 | ADAM17 peptidase | physiologically relevant | NONE | 17344430 | ||
| PMAP | PVAA*SSLR | 190 | ADAM17 peptidase | This_entry_is_based_on_an_experiment. | Gel electrophoresis | 17344430 | ||
| PMAP | PVAA*SSLR | 190 | ADAM19 peptidase | This_entry_is_based_on_an_experiment. | Gel electrophoresis | 17344430 12682046 | ||
| PMAP | PVAA*SSLR | 190 | ADAM8 peptidase | This_entry_is_based_on_an_experiment. | Gel electrophoresis | 17344430 12135759 | ||
| PMAP | PVAA*SSLR | 190 | ADAM33 peptidase | This_entry_is_based_on_an_experiment. | Gel electrophoresis | 17344430 14676211 | ||
| PMAP | PVAA*SSLR | 190 | ADAM9 peptidase | This_entry_is_based_on_an_experiment. | Gel electrophoresis | 17344430 9920899 | ||
| MEROPS | VAAS*SLRN | 191 | ADAM9 peptidase | physiologically relevant | NONE | 17344430 | ||
| PMAP | VAAS*SLRN | 191 | ADAM9 peptidase | This_entry_is_based_on_an_experiment. | Gel electrophoresis | 17344430 9920899 | ||
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| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| NO_DATA | NO_DATA | NO_DATA | |