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|---|---|---|
| UniProt ID |
P20333 |
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| Entry Name |
TNR1B_HUMAN |
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| Protein Name |
Tumor necrosis factor receptor superfamily member 1B |
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| Primary Gene Name |
TNFRSF1B |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function |
Receptor |
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| Membrane Location |
Secreted |
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| Substrate Name | TNFRII | |
| Cell Type | monocytes, lymphocytes | |
| Substrate Description | Leukocyte Recruitment, Cytokines and cytokine receptors involved in cell-cell communication, including firm adhesion | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | Immune and Inflammation; cytokine receptor | |
| Sheddase | ADAM17, NE(neutrophil elastase) | |
| Shedding-related Disease | cytokine receptor | |
| Short Summary of Papers | receptor down-regulation,soluble TNF antagonist | |
| Cleavage Information | NONE | |
| PMID | 16565325 |
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Start | End |
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23 | 257 |
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258 | 287 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | AAHA*LPAQ | 22 | signal peptidase complex (animal) | physiologically relevant | N-terminal sequencing | 2173696 | ||
| PMAP | No_information | ADAM17 peptidase | This entry is based on an experiment | Gel electrophoresis | 15749738 | |||