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|---|---|---|
| UniProt ID |
P20023 |
|
| Entry Name |
CR2_HUMAN |
|
| Protein Name |
Complement receptor type 2 |
|
| Primary Gene Name |
CR2 |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function |
Host cell receptor for virus entry |
|
| Membrane Location |
Cell membrane |
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|---|
| Substrate Name | complement receptor type II (CR2/CD21) | |
| Cell Type | ||
| Substrate Description | receptor for complement C3Dd, receptor for Epstein-Barr virus on human B-cells and T-cells and for HNRPU, B lymphocytes activation. | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | ||
| Sheddase | (unknown) | |
| Shedding-related Disease | cell receptor | |
| Short Summary of Papers | soluble CD21 (sCD21) activates monocytes through binding to membrane CD23 and could potentially bind to its ligands in plasma. the amount of sCD21 in serum could be a modulator of immunity. | |
| Cleavage Information | NONE | |
| PMID | 12938215 |
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|---|
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|---|---|---|
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Start | End |
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21 | 971 |
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972 | 999 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | No_information | (unknown) | 12938215 | |||||