UniProt Summary
UniProt ID

P19256

Entry Name

LFA3_HUMAN

Protein Name

Lymphocyte function-associated antigen 3

Primary Gene Name

CD58

Organism

Homo sapiens (Human)

Molecular Function

Membrane Location

Cell membrane
Membrane




Biological Literature Report of Shedding
Substrate Name LFA3(CD58)
Cell Type
Substrate Description ligand of the T-lymphocyte CD2 glycoprotein.
Substrate Function Category Immune and Inflammation
Substrate Function Subtype
Sheddase (unknown)
Shedding-related Disease ligand
Short Summary of Papers soluble CD58 are released via membrane cleavage mechanism.
Cleavage Information NONE
PMID 9732704



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
Extracellular
29 215
Transmembrane
216 238



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information (unknown) 9732704   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
Sys-BodyFluid Urine 16948836
HCSD cancer(Liver metastasis in colorectal cancer) 23443137