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| UniProt ID |
P17981 |
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| Entry Name |
NAR2A_MOUSE |
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| Protein Name |
T-cell ecto-ADP-ribosyltransferase 1 |
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| Primary Gene Name |
Art2a |
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| Organism |
Mus musculus (Mouse) |
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| Molecular Function |
Hydrolase |
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| Membrane Location |
Cell membrane |
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| Substrate Name | ARTC2 | |
| Cell Type | ||
| Substrate Description | has both NAD+ glycohydrolase and ADP-ribosyltransferase activity. | |
| Substrate Function Category | enzyme | |
| Substrate Function Subtype | ||
| Sheddase | metalloproteinase | |
| Shedding-related Disease | ribosyltransferase | |
| Short Summary of Papers | ARTC2.2 undergoes ectodomain shedding in response to NAD+ released from damaged cells during inflammation. the nucleotide-induced membrane-proximal proteolysis provifr a regulatory mechanism to control the substrate specificity of ARTC2.2 | |
| Cleavage Information | ZNo-Human: | |
| PMID | 26209623 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | No_information | metalloproteinase | 26209623 | |||||
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| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| NO_DATA | NO_DATA | NO_DATA | |