UniProt Summary
UniProt ID

P17927

Entry Name

CR1_HUMAN

Protein Name

Complement receptor type 1

Primary Gene Name

CR1

Organism

Homo sapiens (Human)

Molecular Function

Host cell receptor for virus entry
Receptor
Blood group antigen

Membrane Location

Membrane




Biological Literature Report of Shedding
Substrate Name complement receptor type 1 (C3b-R,CD35)
Cell Type
Substrate Description immune complexes that have activated complement.
Substrate Function Category Immune and Inflammation
Substrate Function Subtype
Sheddase (unknown)
Shedding-related Disease cell receptor
Short Summary of Papers soluble complement receptor type 1 (CD35) is cleavaged and released from leukocytes, may play a role in the control of complement activation at sites of inflammation.
Cleavage Information NONE
PMID 7957565



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
Extracellular
42 1971
Transmembrane
1972 1996



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information (unknown) 7957565   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
SPD 22728825
Sys-BodyFluid Urine 16948836