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| UniProt ID |
P17693 |
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| Entry Name |
HLAG_HUMAN |
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| Protein Name |
HLA class I histocompatibility antigen, alpha chain G |
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| Primary Gene Name |
HLA-G |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function | ||
| Membrane Location |
Secreted |
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| Substrate Name | HLA-G | |
| Cell Type | ||
| Substrate Description | presentation of foreign antigens to the immune system, maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | ||
| Sheddase | metalloproteinase | |
| Shedding-related Disease | cell surface protein | |
| Short Summary of Papers | the shed soluble HLA-G could act as an immunoregulator in NK cell recognition | |
| Cleavage Information | NONE | |
| PMID | 14697234 |
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Start | End |
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25 | 308 |
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309 | 332 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | GKDY*LALN | 147 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | No_information | metalloproteinase | 14697234 | |||||