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| UniProt ID |
P16150 |
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| Entry Name |
LEUK_HUMAN |
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| Protein Name |
Leukosialin |
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| Primary Gene Name |
SPN |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function | ||
| Membrane Location |
Membrane |
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| Substrate Name | Leukosialin(CD43) | |
| Cell Type | ||
| Substrate Description | one of major glycoproteins of thymocytes and T lymphocytes. plays a role in the physicochemical properties of the T-cell surface and in lectin binding. | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | ||
| Sheddase | metalloprotease, serine protease | |
| Shedding-related Disease | cell surface protein | |
| Short Summary of Papers | stimulation of leukocytes cleavge of CD43 from the cell surface | |
| Cleavage Information | NONE | |
| PMID | 7507963 7683406 |
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Start | End |
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20 | 253 |
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254 | 276 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | DALG*STTA | 19 | signal peptidase complex (animal) | physiologically relevant | N-terminal sequencing | 1731338 | ||
| PAPER | No_information | metalloprotease, serine protease | 7507963 | |||||
| PMAP | No_information | presenilin 1 | This entry is based on an experiment | Gel electrophoresis | 15540986 | |||