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|---|---|---|
| UniProt ID |
P15291 |
|
| Entry Name |
B4GT1_HUMAN |
|
| Protein Name |
Beta-1,4-galactosyltransferase 1 |
|
| Primary Gene Name |
B4GALT1 |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function |
Glycosyltransferase |
|
| Membrane Location |
Secreted |
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|---|
| Substrate Name | Galactosyltransferase 1 | |
| Cell Type | ||
| Substrate Description | catalyzes the production of lactose, responsible for the synthesis of complex-type N-linked oligosaccharides. The cell surface form functions as a recognition molecule during a variety of cell to cell and cell to matrix interactions | |
| Substrate Function Category | enzyme | |
| Substrate Function Subtype | ||
| Sheddase | (unknown) | |
| Shedding-related Disease | transferase | |
| Short Summary of Papers | a small fraction of galT moves to the plasma membrane and possibly leaves the cell by shedding. | |
| Cleavage Information | NONE | |
| PMID | 3093147 17021253 |
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Start | End |
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25 | 44 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | SGEL*RTGG | 77 | unknown peptidase | physiologically relevant | Mass spectroscopy | 26796116 | ||
| PAPER | No_information | (unknown) | 3093147 17021253 | |||||
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|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| PAPER | cancer(ovary) | 18560578 | |
| Sys-BodyFluid | Milk | 16502470 | |
| Sys-BodyFluid | Seminal Fluid | 16709260 | |
| Sys-BodyFluid | Amniotic fluid | 17495049 | |
| Sys-BodyFluid | Saliva | 18361515 | |
| Sys-BodyFluid | Cerebrospinal fluid | 17022648 | |
| Sys-BodyFluid | Tear | 16901338 | |
| Sys-BodyFluid | Urine | 16948836 | |
| HCSD | cancer (gastric cancer) | 23161554 | |
| HCSD | cancer (lung cancer) | 19776420 | |
| HCSD | cancer(prostate cancer) | 22908226 | |
| HCSD | cancer(23 cancer cell lines) | 20124221 | |
| HCSD | cancer(Head and neck squamous cell carcinoma) | 23665456 | |
| HCSD | cancer(colorectal cancer | 22408128 | |
| HCSD | cancer(colorectal cancer | 24418523 | |
| HCSD | cancer(head and neck squamous cell carcinoma) | 22918226 | |
| HCSD | cancer(urothelial carcinoma) | 23591195 | |
| HCSD | cancer(glioblastoma multiforme) | 21574646 | |
| HCSD | cancer(pancreatic cancer) | 21625447 | |
| HCSD | cancer(ovarian cancer) | 23805888 | |
| HCSD | cancer(ovarian cancer) | 22623176 | |
| HCSD | cancer(metastatic non-small-cell lung cancer) | 24667143 | |
| HCSD | cancer(Liver metastasis in colorectal cancer) | 23443137 | |
| HCSD | non-small cell lung cancer | 21262398 | |
| HCSD | cancer(non small cell lung cancer) | 19655816 | |
| locate | 17986452 | ||