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|---|---|---|
| UniProt ID |
P15116 |
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| Entry Name |
CADH2_MOUSE |
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| Protein Name |
Cadherin-2 |
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| Primary Gene Name |
Cdh2 |
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| Organism |
Mus musculus (Mouse) |
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| Molecular Function | ||
| Membrane Location |
Cell membrane |
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| Substrate Name | N-cadherin | |
| Cell Type | mouse neuroblastoma N2a cells, human neuroglioma H4 cells | |
| Substrate Description | cell migration; neurite outgrowth | |
| Substrate Function Category | central nervous system (neuron);disease | |
| Substrate Function Subtype | Central nervous system (CNS) pathology; cell adhesion molecules | |
| Sheddase | ADAM10 | |
| Shedding-related Disease | cell adhesion molecule; cancer (prostate) | |
| Short Summary of Papers | release of the extracellular domain, for the regulation of cell adhesion, cell migration. decreased neuronal cell adhesion, increased neurite outgrowth | |
| Cleavage Information | NONE | |
| PMID | 19049889 15692570 18951988 16998833 |
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Start | End |
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160 | 724 |
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725 | 745 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | No_information | ADAM10 | Gel electrophoresis | 15692570 | ||||
| PaperC | No_information | BACE1/2 | Type I TMP | proteomics | 23430253 | |||