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| UniProt ID |
P14210 |
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| Entry Name |
HGF_HUMAN |
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| Protein Name |
Hepatocyte growth factor |
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| Primary Gene Name |
HGF |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function |
Serine protease homolog |
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| Membrane Location | ||
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| Substrate Name | Hepatocyte growth factor (HGF) | |
| Cell Type | ||
| Substrate Description | HGF signaling (physiological processes including proliferation, scattering, morphogenesis and survival) | |
| Substrate Function Category | growth factor & growth hormone | |
| Substrate Function Subtype | growth factor (HGFR) | |
| Sheddase | (unkown) | |
| Shedding-related Disease | growth factor (HGFR) | |
| Short Summary of Papers | convert proHGF to biologically active HGF | |
| Cleavage Information | NONE | |
| PMID | 8117273 |
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Start | End |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | GKGR*SYKG | 134 | coagulation factor Xa | physiologically relevant | N-terminal sequencing | 11832492 | ||
| HPRD | DLHR*HIFW | 424 | Kallikrein B; Coagulation factor XI; | 12372819 | ||||
| HPRD | DLHR*HIFW | 424 | Kallikrein B; Coagulation factor XI; | 12372819 | ||||
| MEROPS | DLHR*HIFW | 424 | plasma kallikrein | physiologically relevant | NONE | 12372819 | ||
| MEROPS | DLHR*HIFW | 424 | coagulation factor XIa | physiologically relevant | NONE | 12372819 | ||
| MEROPS | IVNL*DHPV | 480 | chymase (Homo sapiens-type) | physiologically relevant | NONE | 19073880 | ||
| MEROPS | TKQL*RVVN | 493 | chymase (Homo sapiens-type) | physiologically relevant | Mass spectroscopy | 16303761 | ||
| HPRD | KQLR*VVNG | 494 | Kallikrein B; Matriptase; Coagulation factor XI; | 12372819 10962009 | ||||
| HPRD | KQLR*VVNG | 494 | Kallikrein B; Matriptase; Coagulation factor XI; | 12372819 10962009 | ||||
| MEROPS | KQLR*VVNG | 494 | PCSK4 peptidase | not physiologically relevant | consensus sequence | 18505722 | ||
| MEROPS | KQLR*VVNG | 494 | PCSK6 peptidase | not physiologically relevant | consensus sequence | 18505722 | ||
| MEROPS | KQLR*VVNG | 494 | PCSK5 peptidase | not physiologically relevant | consensus sequence | 18505722 | ||
| MEROPS | KQLR*VVNG | 494 | PCSK7 peptidase | not physiologically relevant | consensus sequence | 18505722 | ||
| MEROPS | KQLR*VVNG | 494 | plasma kallikrein | physiologically relevant | NONE | 12372819 | ||
| MEROPS | KQLR*VVNG | 494 | coagulation factor XIa | physiologically relevant | NONE | 12372819 | ||
| MEROPS | KQLR*VVNG | 494 | hepsin | physiologically relevant | NONE | 15839837 | ||
| MEROPS | KQLR*VVNG | 494 | hepatocyte growth factor activator | physiologically relevant | NONE | NONE | ||
| MEROPS | KQLR*VVNG | 494 | urokinase-type plasminogen activator | physiologically relevant | mutation | 8362987 | ||
| MEROPS | KQLR*VVNG | 494 | matriptase | physiologically relevant | NONE | 17131055 | ||
| PMAP | KQLR*VVNG | 494 | hepsin | This_entry_is_based_on_an_experiment. | N-terminal sequencing | 15839837 | ||
| PMAP | KQLR*VVNG | 494 | coagulation factor XIa | This_entry_is_based_on_an_experiment. | N-terminal sequencing | 12372819 1328193 | ||
| PMAP | KQLR*VVNG | 494 | matriptase | This_entry_is_based_on_an_experiment. | 10962009 | |||
| PMAP | KQLR*VVNG | 494 | u-plasminogen activator | This_entry_is_based_on_an_experiment. | 1334458 | |||
| PMAP | KQLR*VVNG | 494 | hepsin | This_entry_is_based_on_an_experiment. | N-terminal sequencing | 15839837 | ||
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| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| NO_DATA | NO_DATA | NO_DATA | |