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|---|---|---|
| UniProt ID |
P14151 |
|
| Entry Name |
LYAM1_HUMAN |
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| Protein Name |
L-selectin |
|
| Primary Gene Name |
SELL |
|
| Organism |
Homo sapiens (Human) |
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| Molecular Function | ||
| Membrane Location |
Cell membrane |
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| Substrate Name | L-selectin | |
| Cell Type | lymphocytes,monocytes,neutrophils | |
| Substrate Description | Leukocyte Recruitment - Tethering and rolling | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | Immune and Inflammation; cell adhesion molecule | |
| Sheddase | ADAM17 | |
| Shedding-related Disease | cell adhesion molecule | |
| Short Summary of Papers | de-adhesion, increase rolling velocity | |
| Cleavage Information | NONE | |
| PMID | 16565325 9812885 |
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|---|---|---|
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Start | End |
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39 | 332 |
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333 | 355 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | CTFI*CSEG | 288 | astacin | not physiologically relevant | Mass spectroscopy | 21693781 | ||
| MEROPS | KLDK*SFSM | 321 | ADAM17 peptidase | not physiologically relevant | NONE | 9812885 | ||
| PMAP | KLDK*SFSM | 321 | ADAM17 peptidase | This entry is based on an experiment | Others | 9812885 | ||
| PAPER | No_information | ADAM8 | NONE | NONE | 17548643 | |||
| PMAP | No_information | matrix metallopeptidase-3 | This entry is based on an experiment | 8662605 | ||||
| PMAP | No_information | matrix metallopeptidase-1 | This entry is based on an experiment | Others | 8662605 | |||
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|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| Sys-BodyFluid | Urine | 16335936 | |
| Sys-BodyFluid | Plasma/Serum | 18793429 | |
| Sys-BodyFluid | Plasma/Serum | 18795103 | |
| Sys-BodyFluid | Plasma/Serum | 16104056 | |
| Sys-BodyFluid | Plasma/Serum | 16739989 | |
| Sys-BodyFluid | Plasma/Serum | 14718574 | |
| Sys-BodyFluid | Plasma/Serum | 15822942 | |
| HCSD | cancer(prostate cancer) | 22908226 | |