UniProt Summary
UniProt ID

P13721

Entry Name

SIAT1_RAT

Protein Name

Beta-galactoside alpha-2,6-sialyltransferase 1

Primary Gene Name

St6gal1

Organism

Rattus norvegicus (Rat)

Molecular Function

Transferase
Glycosyltransferase

Membrane Location

Secreted
Membrane




Biological Literature Report of Shedding
Substrate Name beta-galactoside alpha-2,6-sialyltransferase 1
Cell Type
Substrate Description transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates
Substrate Function Category enzyme
Substrate Function Subtype
Sheddase cathepsin D-like proteinase
Shedding-related Disease transferase
Short Summary of Papers GalBeta1-4GlcNAc alpha-2,6-sialyltransferase cleaved by cathepsin D-like proteinase and released during the acute-phase response
Cleavage Information ZNo-Human:
PMID 2505760



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
Transmembrane
10 26



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information cathepsin D-like proteinase 2505760   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
SPD 22728825