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| UniProt ID |
P13591 |
|
| Entry Name |
NCAM1_HUMAN |
|
| Protein Name |
Neural cell adhesion molecule 1 |
|
| Primary Gene Name |
NCAM1 |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function |
Host cell receptor for virus entry |
|
| Membrane Location |
Secreted |
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|---|
| Substrate Name | NCAM-1 | |
| Cell Type | ||
| Substrate Description | cell migration; neurite outgrowth | |
| Substrate Function Category | central nervous system (neuron) | |
| Substrate Function Subtype | Central nervous system (CNS) pathology; cell adhesion molecules | |
| Sheddase | metalloproteinase | |
| Shedding-related Disease | cell adhesion molecule | |
| Short Summary of Papers | shedding of NCAM regulates NCAM-mediated neurite outgrowth. | |
| Cleavage Information | NONE | |
| PMID | 15884014 |
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Start | End |
|
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20 | 718 |
|
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719 | 739 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | TAVS*LQVD | 19 | UNKNOWN | Mass spectrometry | 33796845    | |||
| ASCENT | LTIY*NANI | 84 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314    | |||
| ASCENT | LMFK*NAPT | 121 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314    | |||
| PAPER | LMFK*NAPT | 121 | UNKNOWN | Mass spectrometry | 33796845    | |||
| ASCENT | LNGK*GLGE | 592 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314    | |||
| ASCENT | SEFK*TQPV | 604 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314    | |||
| ASCENT | YRAL*SSEW | 652 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314    | |||
| ASCENT | GKSK*AAHF | 694 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314    | |||
| PAPER | No_information | metalloproteinase | 15884014    | |||||
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|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| PAPER | ovary | 15815987 | |
| Sys-BodyFluid | Plasma/Serum | 18795103 | |
| Sys-BodyFluid | Cerebrospinal fluid | 17853512 | |
| Sys-BodyFluid | Cerebrospinal fluid | 18052119 | |
| Sys-BodyFluid | Cerebrospinal fluid | 15582749 | |
| Sys-BodyFluid | Plasma/Serum | 18793429 | |
| Sys-BodyFluid | Plasma/Serum | 16104056 | |
| Sys-BodyFluid | Plasma/Serum | 16739989 | |
| Sys-BodyFluid | Plasma/Serum | 14718574 | |
| Sys-BodyFluid | Cerebrospinal fluid | 15952730 | |
| Sys-BodyFluid | Urine | 16948836 | |
| Sys-BodyFluid | Cerebrospinal fluid | 17022648 | |
| HCSD | cancer (lung cancer) | 19776420 | |
| HCSD | cancer(Head and neck squamous cell carcinoma) | 23665456 | |
| HCSD | cancer(colorectal cancer | 24418523 | |
| HCSD | cancer(ovarian cancer) | 23805888 | |
| HCSD | cancer(ovarian cancer) | 22623176 | |