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UniProt ID |
P13591 |
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Entry Name |
NCAM1_HUMAN |
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Protein Name |
Neural cell adhesion molecule 1 |
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Primary Gene Name |
NCAM1 |
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Organism |
Homo sapiens (Human) |
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Molecular Function |
Host cell receptor for virus entry |
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Membrane Location |
Secreted |
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Substrate Name | NCAM-1 | |
Cell Type | ||
Substrate Description | cell migration; neurite outgrowth | |
Substrate Function Category | central nervous system (neuron) | |
Substrate Function Subtype | Central nervous system (CNS) pathology; cell adhesion molecules | |
Sheddase | metalloproteinase | |
Shedding-related Disease | cell adhesion molecule | |
Short Summary of Papers | shedding of NCAM regulates NCAM-mediated neurite outgrowth. | |
Cleavage Information | NONE | |
PMID | 15884014 |
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Start | End |
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20 | 718 |
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719 | 739 |
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Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
PAPER | TAVS*LQVD | 19 | UNKNOWN | Mass spectrometry | 33796845    | |||
ASCENT | LTIY*NANI | 84 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314    | |||
ASCENT | LMFK*NAPT | 121 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314    | |||
PAPER | LMFK*NAPT | 121 | UNKNOWN | Mass spectrometry | 33796845    | |||
ASCENT | LNGK*GLGE | 592 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314    | |||
ASCENT | SEFK*TQPV | 604 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314    | |||
ASCENT | YRAL*SSEW | 652 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314    | |||
ASCENT | GKSK*AAHF | 694 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314    | |||
PAPER | No_information | metalloproteinase | 15884014    |
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Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
PAPER | ovary | 15815987 | |
Sys-BodyFluid | Plasma/Serum | 18795103 | |
Sys-BodyFluid | Cerebrospinal fluid | 17853512 | |
Sys-BodyFluid | Cerebrospinal fluid | 18052119 | |
Sys-BodyFluid | Cerebrospinal fluid | 15582749 | |
Sys-BodyFluid | Plasma/Serum | 18793429 | |
Sys-BodyFluid | Plasma/Serum | 16104056 | |
Sys-BodyFluid | Plasma/Serum | 16739989 | |
Sys-BodyFluid | Plasma/Serum | 14718574 | |
Sys-BodyFluid | Cerebrospinal fluid | 15952730 | |
Sys-BodyFluid | Urine | 16948836 | |
Sys-BodyFluid | Cerebrospinal fluid | 17022648 | |
HCSD | cancer (lung cancer) | 19776420 | |
HCSD | cancer(Head and neck squamous cell carcinoma) | 23665456 | |
HCSD | cancer(colorectal cancer | 24418523 | |
HCSD | cancer(ovarian cancer) | 23805888 | |
HCSD | cancer(ovarian cancer) | 22623176 |