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UniProt ID |
P11627 |
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Entry Name |
L1CAM_MOUSE |
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Protein Name |
Neural cell adhesion molecule L1 |
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Primary Gene Name |
L1cam |
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Organism |
Mus musculus (Mouse) |
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Molecular Function |
Developmental protein |
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Membrane Location |
Cell membrane |
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Substrate Name | L1 (neural cell adhesion molecule L1) | |
Cell Type | CHO cells | |
Substrate Description | cell migration; neurite outgrowth | |
Substrate Function Category | central nervous system (neuron) | |
Substrate Function Subtype | Central nervous system (CNS) pathology; cell adhesion molecules | |
Sheddase | ADAM10 | |
Shedding-related Disease | cell adhesion molecule | |
Short Summary of Papers | shedding of L1 is necessary to promote migration. | |
Cleavage Information | NONE | |
PMID | 11706054 18951988 |
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Start | End |
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20 | 1123 |
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1124 | 1146 |
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Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
MEROPS | PCLL*IQIP | 19 | signal peptidase complex (animal) | physiologically relevant | Mass spectroscopy | 16457602    | ||
MEROPS | HSKR*HIHK | 863 | PCSK5 peptidase | physiologically relevant | NONE | 12529374    | ||
PaperC | No_information | BACE1 | Type I | proteomics | 22728825    | |||
PMAP | No_information | presenilin 1 | This_entry_is_based_on_an_experiment. | Gel electrophoresis | 16199880    | |||
PMAP | No_information | ADAM10 peptidase | This_entry_is_based_on_an_experiment. | 16199880    |