UniProt Summary
UniProt ID

P0C192

Entry Name

LRC4B_MOUSE

Protein Name

Leucine-rich repeat-containing protein 4B

Primary Gene Name

Lrrc4b

Organism

Mus musculus (Mouse)

Molecular Function

Membrane Location

Cell membrane
Membrane




Biological Literature Report of Shedding
Substrate Name Netrin-G3 ligand(Lrig4)
Cell Type
Substrate Description synaptic adhesion protein. regulates the formation of excitatory synapses.
Substrate Function Category central nervous system (neuron)
Substrate Function Subtype
Sheddase metalloproteinase
Shedding-related Disease ligand
Short Summary of Papers (null)NGL-3 is a novel substrate of MMPs and γ-secretase and that NGL-3 cleavage may regulate synaptic adhesion during long-term depression
Cleavage Information ZNo-Human:
PMID 24298159



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
Transmembrane
575 595



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information metalloproteinase 24298159   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
PAPER neuron 22728825