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| UniProt ID |
P09326 |
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| Entry Name |
CD48_HUMAN |
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| Protein Name |
CD48 antigen |
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| Primary Gene Name |
CD48 |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function | ||
| Membrane Location |
Cell membrane |
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| Substrate Name | CD48 | |
| Cell Type | ||
| Substrate Description | ligand for CD2. might facilitate interaction between activated lymphocytes involved in regulating T-cell activation. | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | ||
| Sheddase | (unknown) | |
| Shedding-related Disease | ligand | |
| Short Summary of Papers | GPI-anchored CD48 may be cleaved CD48 may be cleaved after activation, explaining the existence of soluble CD48 in circulation. the soluble CD48 is detected at elevated levels in the plasma of patients with lymphoproliferative disease, arthritis, and acute EBV infection. | |
| Cleavage Information | GPI-anchor | |
| PMID | 20833258 9418191 11513145 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | No_information | (unknown) | 20833258 9418191 11513145 | |||||
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| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| HCSD | cancer(23 cancer cell lines) | 20124221 | |