UniProt Summary
UniProt ID

P08865

Entry Name

RSSA_HUMAN

Protein Name

40S ribosomal protein SA

Primary Gene Name

RPSA

Organism

Homo sapiens (Human)

Molecular Function

Host cell receptor for virus entry
Ribosomal protein
Receptor
Ribonucleoprotein

Membrane Location

Cell membrane
Membrane




Biological Literature Report of Shedding
Substrate Name 67-kD laminin receptor (67LR)
Cell Type
Substrate Description cell surface receptor for laminin. cell adhesion to the basement membrane. cell fate determination and tissue morphogenesis
Substrate Function Category disease
Substrate Function Subtype
Sheddase MMP2
Shedding-related Disease cancer (tumor invasion)
Short Summary of Papers the shed soluble 67LR may result in conformational changes and proteolytic cleavage of laminin, and promote tumor cell migration
Cleavage Information NONE
PMID 8655633



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
NO_INFO



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER No_information MMP2 8655633   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
Sys-BodyFluid Plasma/Serum 16083276
Sys-BodyFluid Plasma/Serum 16104056
Sys-BodyFluid Plasma/Serum 17877382
Sys-BodyFluid Tear 16901338
Sys-BodyFluid Saliva 17614365
Sys-BodyFluid Seminal Fluid 16709260
HCSD cancer (gastric cancer) 23161554
HCSD cancer (lung cancer) 19776420
HCSD cancer(prostate cancer) 22908226
HCSD cancer(Head and neck squamous cell carcinoma) 23665456
HCSD cancer(colon tumor) 23684732
HCSD cancer(colorectal cancer 22408128
HCSD cancer(colorectal carsinoma) 23585443
HCSD cancer(colorectal cancer 24418523
HCSD cancer(head and neck squamous cell carcinoma) 22918226
HCSD cancer(urothelial carcinoma) 23591195
HCSD cancer(glioblastoma multiforme) 21574646
HCSD cancer(lung adenocarcinoma) 22896658
HCSD cancer(pancreatic cancer) 21625447
HCSD cancer(ovarian cancer) 23805888
HCSD cancer(oral cancer ) 21714544
HCSD cancer(lung cancer) 21186846
HCSD cancer(Liver metastasis in colorectal cancer) 23443137
HCSD cancer(colorectal cancer) 24681409