|
|
||
|---|---|---|
| UniProt ID |
P08571 |
|
| Entry Name |
CD14_HUMAN |
|
| Protein Name |
Monocyte differentiation antigen CD14 |
|
| Primary Gene Name |
CD14 |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function | ||
| Membrane Location |
Secreted |
|
|
|
|---|
| Substrate Name | LPS-R (CD14) | |
| Cell Type | ||
| Substrate Description | receptor for LPS binding protein/LPS complex. mediating the innate immune response to bacterial lipopolysaccharide (LPS) | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | ||
| Sheddase | (unknown) | |
| Shedding-related Disease | cell receptor | |
| Short Summary of Papers | CD14 shedding induced by monocyte stimulation may play an important role in the regulationof surface CD14 expression. | |
| Cleavage Information | GPI-anchor | |
| PMID | 1880416 |
|
|
|---|
|
|
||
|---|---|---|
|
|
Start | End |
|
|
||
|
|
||||||||
|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | HVSA*TTPE | 19 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | No_information | (unknown) | 1880416 | |||||
| PMAP | No_information | gingipain R | This_entry_is_based_on_an_experiment. | Gel electrophoresis | 12011031 | |||
| PMAP | No_information | gingipain R | This_entry_is_based_on_an_experiment. | Gel electrophoresis | 12011031 | |||
|
|
|||
|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| PAPER | platelet | 20962327 | |
| SPD | 22728825 | ||
| Sys-BodyFluid | Milk | 16502470 | |
| Sys-BodyFluid | Seminal Fluid | 16709260 | |
| Sys-BodyFluid | Amniotic fluid | 17373841 | |
| Sys-BodyFluid | Amniotic fluid | 17495049 | |
| Sys-BodyFluid | Nipple aspiration fluid | 12889602 | |
| Sys-BodyFluid | Saliva | 17614365 | |
| Sys-BodyFluid | Saliva | 18361515 | |
| Sys-BodyFluid | Cerebrospinal fluid | 17853512 | |
| Sys-BodyFluid | Cerebrospinal fluid | 18052119 | |
| Sys-BodyFluid | Cerebrospinal fluid | 17022648 | |
| Sys-BodyFluid | Cerebrospinal fluid | 15582749 | |
| Sys-BodyFluid | Cerebrospinal fluid | 14998169 | |
| Sys-BodyFluid | Tear | 16901338 | |
| Sys-BodyFluid | Urine | 17022654 | |
| Sys-BodyFluid | Urine | 11680902 | |
| Sys-BodyFluid | Urine | 16335936 | |
| Sys-BodyFluid | Urine | 15048996 | |
| Sys-BodyFluid | Urine | 16281181 | |
| Sys-BodyFluid | Urine | 16948836 | |
| Sys-BodyFluid | Plasma/Serum | 18793429 | |
| Sys-BodyFluid | Plasma/Serum | 18795103 | |
| Sys-BodyFluid | Plasma/Serum | 17877382 | |
| Sys-BodyFluid | Plasma/Serum | 16944932 | |
| Sys-BodyFluid | Plasma/Serum | 16104056 | |
| Sys-BodyFluid | Plasma/Serum | 17553692 | |
| Sys-BodyFluid | Plasma/Serum | 16739989 | |
| Sys-BodyFluid | Plasma/Serum | 16083276 | |
| Sys-BodyFluid | Plasma/Serum | 14718574 | |
| HCSD | cancer (lung cancer) | 19776420 | |
| HCSD | cancer(23 cancer cell lines) | 20124221 | |
| HCSD | cancer(Head and neck squamous cell carcinoma) | 23665456 | |
| HCSD | cancer(colorectal cancer | 24418523 | |
| HCSD | cancer(pancreatic cancer) | 21625447 | |
| HCSD | cancer(ovarian cancer) | 22623176 | |
| HCSD | cancer(colorectal cancer) | 22506683 | |
| locate | 17986452 | ||
| HCSD | cancer(colorectal cancer) | 25216327 | |
| HCSD | cancer(lung cancer) | 21806062 | |