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| UniProt ID |
P08138 |
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| Entry Name |
TNR16_HUMAN |
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| Protein Name |
Tumor necrosis factor receptor superfamily member 16 |
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| Primary Gene Name |
NGFR |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function |
Developmental protein |
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| Membrane Location |
Cell membrane |
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| Substrate Name | p75NTR (NGFR,TNFRSF16) | |
| Cell Type | ||
| Substrate Description | diverse signaling in survival and apoptosis | |
| Substrate Function Category | growth factor & growth hormone | |
| Substrate Function Subtype | growth factor receptor (neurotrophin) | |
| Sheddase | ADAM17 | |
| Shedding-related Disease | growth factor receptor (NGFR) | |
| Short Summary of Papers | ectodomain shedding result in RIP (regulated intramembrane proteolysis), regulate cell apoptosis | |
| Cleavage Information | NONE | |
| PMID | 14638693 17904861 |
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Start | End |
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29 | 250 |
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251 | 272 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| ASCENT | LQSM*SAPC | 95 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| ASCENT | LQSM*SAPC | 95 | UNKNOWN | subtiligase-based N-terminal sequencing | 33536314 | |||
| PAPER | SILA*AVVV | 260 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PMAP | No_information | ADAM17 peptidase | This entry is based on an experiment | Gel electrophoresis | 17904861 | |||