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|---|---|---|
| UniProt ID |
P07333 |
|
| Entry Name |
CSF1R_HUMAN |
|
| Protein Name |
Macrophage colony-stimulating factor 1 receptor |
|
| Primary Gene Name |
CSF1R |
|
| Organism |
Homo sapiens (Human) |
|
| Molecular Function |
Kinase |
|
| Membrane Location |
Cell membrane |
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|---|
| Substrate Name | CSF1R(fms) | |
| Cell Type | macrophage, monocytes | |
| Substrate Description | hematopoietic regulation in cell survival, proliferation and differentiation | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | Immune and Inflammation; cytokine receptor (hematopoietic) | |
| Sheddase | ADAM17 | |
| Shedding-related Disease | cytokine receptor | |
| Short Summary of Papers | shedding of CSF-1R, down-modulation in mononuclear phagocytes undergoing activation | |
| Cleavage Information | NONE | |
| PMID | 11160199 |
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|---|---|---|
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Start | End |
|
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20 | 517 |
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518 | 538 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | No_information | metalloproteinase | 19890054 | |||||
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|---|---|---|---|
| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| SPD | 22728825 | ||
| Sys-BodyFluid | Amniotic fluid | 17373841 | |
| Sys-BodyFluid | Amniotic fluid | 17495049 | |
| Sys-BodyFluid | Cerebrospinal fluid | 18052119 | |
| Sys-BodyFluid | Cerebrospinal fluid | 17022648 | |
| Sys-BodyFluid | Urine | 16948836 | |
| Sys-BodyFluid | Plasma/Serum | 18793429 | |
| Sys-BodyFluid | Plasma/Serum | 18795103 | |
| Sys-BodyFluid | Plasma/Serum | 16104056 | |
| Sys-BodyFluid | Plasma/Serum | 17553692 | |
| Sys-BodyFluid | Plasma/Serum | 16739989 | |