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|---|---|---|
| UniProt ID |
P07141 |
|
| Entry Name |
CSF1_MOUSE |
|
| Protein Name |
Macrophage colony-stimulating factor 1 |
|
| Primary Gene Name |
Csf1 |
|
| Organism |
Mus musculus (Mouse) |
|
| Molecular Function |
Cytokine |
|
| Membrane Location |
Secreted |
|
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|---|
| Substrate Name | CSF-1 | |
| Cell Type | macrophage, monocytes | |
| Substrate Description | hematopoietic regulation in cell survival, proliferation and differentiation | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | Immune and Inflammation; cytokine (hematopoietic) | |
| Sheddase | ADAM17 | |
| Shedding-related Disease | cytokine | |
| Short Summary of Papers | shedding generate soluble CSF-1 form and regulate bioavailability of CSF-1 | |
| Cleavage Information | NONE | |
| PMID | 17982061 |
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|---|---|---|
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Start | End |
|
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33 | 492 |
|
|
493 | 515 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | RSIA*KEVS | 32 | signal peptidase complex (animal) | physiologically relevant | N-terminal sequencing | 3925458 | ||
| PAPER | No_information | ADAM17 | This_entry_is_based_on_an_experiment. | 17982061 | ||||