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| UniProt ID |
P05362 |
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| Entry Name |
ICAM1_HUMAN |
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| Protein Name |
Intercellular adhesion molecule 1 |
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| Primary Gene Name |
ICAM1 |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function |
Host cell receptor for virus entry |
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| Membrane Location |
Membrane |
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| Substrate Name | ICAM-1 | |
| Cell Type | endothelial cell, monocytes, lymphocytes | |
| Substrate Description | Leukocyte Recruitment , Firm adhesion and locomotion to the endothelial cell junction | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | Immune and Inflammation-Leukocyte Recruitment | |
| Sheddase | NE(neutrophil elastase), ADAM17 | |
| Shedding-related Disease | cell adhesion molecule | |
| Short Summary of Papers | de-adhesion,soluble adhesion and integrin antagonist | |
| Cleavage Information | NONE | |
| PMID | 16565325 16332693 |
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Start | End |
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28 | 480 |
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481 | 503 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | FSAK*ASVS | 273 | UNKNOWN | Mass spectrometry | 33796845 | |||
| PAPER | No_information | (unkown) | 1684377 | |||||
| PMAP | No_information | gingipain R2 | This entry is based on an experiment | Gel electrophoresis | 14514759 | |||
| PMAP | No_information | gingipain R1 | This entry is based on an experiment | Gel electrophoresis | 14514759 | |||
| PMAP | No_information | gingipain K | This entry is based on an experiment | Gel electrophoresis | 14514759 | |||
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| Secretome Database | Cell Type or Body Fluid | PubMed Reference | |
| SPD | 22728825 | ||
| Sys-BodyFluid | Amniotic fluid | 17373841 | |
| Sys-BodyFluid | Amniotic fluid | 17495049 | |
| Sys-BodyFluid | Bronchoalveolar lavage fluid | 16497942 | |
| Sys-BodyFluid | Urine | 16948836 | |
| Sys-BodyFluid | Plasma/Serum | 18793429 | |
| Sys-BodyFluid | Plasma/Serum | 16104056 | |
| Sys-BodyFluid | Plasma/Serum | 17553692 | |
| Sys-BodyFluid | Plasma/Serum | 14718574 | |
| HCSD | cancer (lung cancer) | 19776420 | |
| HCSD | cancer(prostate cancer) | 22908226 | |
| HCSD | cancer(23 cancer cell lines) | 20124221 | |
| HCSD | cancer(Head and neck squamous cell carcinoma) | 23665456 | |
| HCSD | cancer(colorectal cancer | 24418523 | |
| HCSD | cancer(breast cancer) | 24505115 | |
| HCSD | cancer(pancreatic cancer) | 21625447 | |
| HCSD | cancer(ovarian cancer) | 23805888 | |
| HCSD | cancer(ovarian cancer) | 22623176 | |
| HCSD | cancer(Liver metastasis in colorectal cancer) | 23443137 | |