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| UniProt ID |
P05107 |
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| Entry Name |
ITB2_HUMAN |
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| Protein Name |
Integrin beta-2 |
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| Primary Gene Name |
ITGB2 |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function |
Receptor |
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| Membrane Location |
Cell membrane |
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| Substrate Name | Integrin beta-2(CD18) | |
| Cell Type | ||
| Substrate Description | leukocyte adhesion; neutrophil transmigration | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | Immune and Inflammation; receptor (CAM) | |
| Sheddase | MMP9, | |
| Shedding-related Disease | cytokine receptor | |
| Short Summary of Papers | shedding may modulate the activity of natural killer cells and affect macrophage recruitment during inflammation | |
| Cleavage Information | NONE | |
| PMID | 8692946 |
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Start | End |
|
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23 | 700 |
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701 | 723 |
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|---|---|---|---|---|---|---|---|---|
| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PMAP | EKLK*SQWN | 744 | calpain-2 | This entry is based on an experiment | 10571053 | |||
| PMAP | NPLF*KSAT | 754 | calpain-2 | This entry is based on an experiment | 10571053 | |||
| PMAP | TTVM*NPKF | 762 | calpain-2 | This entry is based on an experiment | 10571053 | |||
| PMAP | MNPK*FAES | 765 | cathepsin X | This entry is based on an experiment | Others | 18701767 | ||
| PMAP | NPKF*AES | 766 | cathepsin X | This entry is based on an experiment | Others | 18701767 | ||
| PMAP | PKFA*ES | 767 | cathepsin X | This entry is based on an experiment | Others | 18701767 | ||
| PMAP | KFAE*S | 768 | cathepsin X | This entry is based on an experiment | Others | 18701767 | ||
| PAPER | NVAA*IVGG | 703* | MMP9, | 8692946 | ||||
| PMAP | No_information | Sat peptidase | This entry is based on an experiment | Gel electrophoresis | 16954394 | |||