UniProt Summary
UniProt ID

P02686

Entry Name

MBP_HUMAN

Protein Name

Myelin basic protein

Primary Gene Name

MBP

Organism

Homo sapiens (Human)

Molecular Function

Membrane Location

Cell membrane
Membrane




Biological Literature Report of Shedding
Substrate Name myelin basic protein (mbp)
Cell Type
Substrate Description myelination of nerves
Substrate Function Category central nervous system (neuron)
Substrate Function Subtype Central nervous system (CNS) pathology; myelin membrane
Sheddase metalloproteinase
Shedding-related Disease cell surface protein
Short Summary of Papers (author suggest) the myelin-associated metalloproteinase could play roles in both myelinogenesis and in pathological demyelination
Cleavage Information NONE
PMID 2600084



Cleavage Site Diagram



Topological Domains
Topological Domains
Start End
NO_INFO



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID
PAPER RTAH*YGSL 202 ADAM17 NONE 26554003   
PAPER GSLP*QKSH 207 ADAM12 NONE 26554003   



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
PAPER platelet 20962327
Sys-BodyFluid Cerebrospinal fluid 14998169
Sys-BodyFluid Plasma/Serum 16104056
Sys-BodyFluid Plasma/Serum 14718574