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| UniProt ID |
O75015 |
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| Entry Name |
FCG3B_HUMAN |
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| Protein Name |
Low affinity immunoglobulin gamma Fc region receptor III-B |
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| Primary Gene Name |
FCGR3B |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function |
IgG-binding protein |
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| Membrane Location |
Secreted |
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| Substrate Name | Fc-gamma RIIIb (CD16B) | |
| Cell Type | ||
| Substrate Description | receptor for the Fc region of immunoglobulins gamma, trap for immune complexes in the peripheral circulation | |
| Substrate Function Category | Immune and Inflammation | |
| Substrate Function Subtype | ||
| Sheddase | ADAM17 | |
| Shedding-related Disease | cell receptor | |
| Short Summary of Papers | ectodomain shedding of CD16b by ADAM17 may be a regulatory mechanism involved in neutrophil activation and neutrophil apoptosis | |
| Cleavage Information | GPI-anchor | |
| PMID | 23228566 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| PAPER | No_information | ADAM17 | 23228566 | |||||