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| UniProt ID |
O43155 |
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| Entry Name |
FLRT2_HUMAN |
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| Protein Name |
Leucine-rich repeat transmembrane protein FLRT2 |
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| Primary Gene Name |
FLRT2 |
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| Organism |
Homo sapiens (Human) |
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| Molecular Function |
Developmental protein |
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| Membrane Location |
Secreted |
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| Substrate Name | FLRT2 | |
| Cell Type | ||
| Substrate Description | cell adhesion, cell migration and axon guidance | |
| Substrate Function Category | central nervous system (neuron) | |
| Substrate Function Subtype | Central nervous system (CNS) pathology; cell adhesion molecules | |
| Sheddase | metalloprotease | |
| Shedding-related Disease | cell adhesion molecule | |
| Short Summary of Papers | FLRT2/3 are shed from neurons and act as repulsive guidance molecules for axons and somata of Unc5-positive neurons. | |
| Cleavage Information | NONE | |
| PMID | 21673655 |
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Start | End |
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36 | 541 |
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542 | 562 |
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| Database | CutSeq | Mapped Position | Protease | Type | Evidence | PMID | ||
| MEROPS | KLLA*CPSV | 35 | signal peptidase complex (animal) | physiologically relevant | N-terminal sequencing | 15340161 | ||
| PAPER | No_information | metalloprotease | 21673655 | |||||