UniProt Summary Literature Review Cleavage Sites Topological Domains Proteolytic Cleavage Secretome Detection
UniProt Summary
UniProt ID

D3ZGQ0
Entry Name

D3ZGQ0_RAT
Protein Name

Interleukin 17 receptor D
Primary Gene Name

Il17rd
Organism

Rattus norvegicus (Rat)
Molecular Function

Membrane Location

Membrane



Biological Literature Report of Shedding
Substrate Name interleukin-17 receptor D
Cell Type RAW 264.7 mouse macrophages, U937 human monocytes, and HEK293T, COS-7, and HeLa cell lines
Substrate Description
Substrate Function Category
Substrate Function Subtype
Sheddase ADAM17
Shedding-related Disease rheumatoid arthritis
Short Summary of Papers ectodomain shedding of IL-17RD in rheumatoid arthritis increases the TNF-alpha-induced inflammatory response
Cleavage Information
PMID 32963355



Cleavage Site Diagram



Topological Domains
Topological Domains
 		Start End
NO_INFO



Proteolytic Cleavage
Database CutSeq Mapped Position Protease Type Evidence PMID



Secretome Detection
Secretome Database Cell Type or Body Fluid PubMed Reference
NO_DATA NO_DATA NO_DATA